The LARS Collaborative are working to validate a new LARS Patient Reported Outcome Measure. We are currently approaching the final stages of Phase One Validation and hope to move forward with Phase Two Validation in 2025.
The goal of our international, multi-site study study is to assess the outcomes of an online, nurse-led, North American transanal irrigation program for LARS on quality of life and bowel function. We hypothesize that TAI, taught and supported through an online portal dedicated to LARS patients, will positively impact quality of life and improve LARS symptoms and scores. We hope that the results of this trial will allow TAI to become part of the standard armamentarium that clinicians offer patients for LARS.
We are conducting a cross-sectional cohort study at Cleveland Clinic Florida to identify and characterize the burden of rectal cancer treatment sequelae in rectal cancer survivors. Using validated and robust Patient Reported Outcome Measures (PROMs), we will investigate the presence and severity of bowel, urinary and sexual dysfunction, as well as emotional and financial distress and identify specific individual factors that are associated with these sequalae. We will also assess survivors’ quality of life.
This is a multicenter, international, prospective, longitudinal cohort study to characterize the long-term functional outcomes and quality of life following rectal cancer treatment, using patient-reported outcome measures (PROMs) with the primary site at the Cleveland Clinic Florida in Weston, FL, USA.
The objective of this study is to characterize the experience of early LARS within the first 3 months following ostomy closure. We will achieve this objective by interviewing patients to collect specific patient queries that patients often have about LARS within this time period. The patient queries collected as part of this study will also be used to inform the creation of a LARS-AI tool, which will aim to provide patients with real-time education and support following ostomy closure.
Pathway of Low Anterior Resection syndrome relief after Surgery (POLARiS) feasibility trial protocol: a multicentre, feasibility cohort study with embedded randomised control trial to compare sacral neuromodulation and transanal irrigation to optimised conservative management in the management of major low anterior resection syndrome following rectal cancer treatment
To learn more about how you can get involved, email us at getinvolved@lars-collaborative.org.
We are here to answer your questions, provide support, and connect you with resources to help you better understand and manage Low Anterior Resection Syndrome (LARS). Feel free to reach out through the following channels:
General Inquiries
For general questions or feedback, please email us at info@lars-collaborative.org.
Steering Committee Contact
If you would like to reach out to a specific member of our steering committee, please mention their name in your email, and we will forward your message to them.
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